English: Pap smear -Multinucleated giant cell representing infection by Herpes simplex virus.The cell is multinucleated and the nuclei appear moulded (lost the normal round contour and flattened where they are in contact with each other,i.e moulded like clay balls pressed together).The virus replicates inside the nucleus and pushes the chromatin of the nucleus to its periphery(seen as a dark rim near nuclear membrane i.e Margination of chromatin).